
IF YOU BUILD IT, (The Grants) will come
Pubmed
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PUBMED
Keyvani Chahi A, Belew MS, Xu J, Chen HTT, Rentas S, Voisin V, Krivdova G, Lechman E, Marhon SA, De Carvalho DD, Dick JE, Bader GD, Hope KJ. PLAG1 dampens protein synthesis to promote human hematopoietic stem cell self-renewal. Blood. 2022 Sep 1;140(9):992-1008. doi: 10.1182/blood.2021014698. PubMed PMID: 35639948; PubMed Central PMCID: PMC9437713.
Pubmed
Krivdova G, Voisin V, Schoof EM, Marhon SA, Murison A, McLeod JL, Gabra MM, Zeng AGX, Aigner S, Yee BA, Shishkin AA, Van Nostrand EL, Hermans KG, Trotman-Grant AC, Mbong N, Kennedy JA, Gan OI, Wagenblast E, De Carvalho DD, Salmena L, Minden MD, Bader GD, Yeo GW, Dick JE, Lechman ER. Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t(8;21) AML. Cell Rep. 2022 Mar 8;38(10):110481. doi: 10.1016/j.celrep.2022.110481. PubMed PMID: 35263585; PubMed Central PMCID: PMC11185845.
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Subedi A, Liu Q, Ayyathan DM, Sharon D, Cathelin S, Hosseini M, Xu C, Voisin V, Bader GD, D’Alessandro A, Lechman ER, Dick JE, Minden MD, Wang JCY, Chan SM. Nicotinamide phosphoribosyltransferase inhibitors selectively induce apoptosis of AML stem cells by disrupting lipid homeostasis. Cell Stem Cell. 2021 Oct 7;28(10):1851-1867.e8. doi: 10.1016/j.stem.2021.06.004. Epub 2021 Jul 21. PubMed PMID: 34293334.